Mar 21, 2010

SCIENCE NEWS - Taste is not just for the tongue

Scientists are discovering that TASTE is a whole-body sensation. There are taste cells in the stomach, intestine and, evidence suggests, the pancreas, colon and esophagus. These sensory cells are part of an ancient battalion tasked with guiding food choices since long before nutrition labels, Rachael Ray or even agriculture existed. While taste cells in the mouth make snap judgments about what should be let inside, new work suggests that gut taste cells serve as specialized ground forces, charged with preparing the digestive system for the aftermath of the tongue’s decisions.

Stimulating these gut cells triggers a complex series of events that can dial down, or amp up, the digestion and absorption of the body’s fuel. When hit by bitter — potentially toxic — substances, gut taste cells sound an alarm that may lead to slower absorption or spur vomiting. And when the gut’s taste sensors encounter something sweet, they send a “prepare for fuel” missive that results in cranked-up insulin levels in the blood.

Though scientists don’t fully understand what follows, studies hint at a tantalizing, if convoluted, connection between gut taste cell activity and metabolism. Figuring out such connections may one day lead to new therapies for treating type 2 diabetes, obesity and other disorders. And the sweet-focused research could help explain recent counter-intuitive findings that link such problems with drinking diet soda.

Diet drinks are often enjoyed without food, which means the gut may be preparing for fuel that never arrives.

So beware those little white lies. Thousands of years of evolution have yielded a finely tuned digestive machine, one that recognizes incoming energy and knows how to make the most of it. These intricate chains of events evolved during a time when that sweet zing reliably indicated food rich in valuable calories. And for thousands of years, the gut reacted appropriately.

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